Santa Clara is a city in the province of Santa Clara, California. The population of the city is over 116,000, making it San Francisco Bay Area's ninth most populous city. Located on San Francisco Bay's southern coast immediately west of San Jose and 45 miles southeast of San Francisco. Located in the heart of Silicon Valley, Santa Clara is home to the headquarters of many high-tech firms including Intel. It also houses Santa Clara University, the oldest higher learning institution in the state of California, the home of San Francisco 49ers of the National Football League, located in the area. Santa Clara has a total area of 18 miles.