Detriot's the largest and most populous city in the U.S. state of Michigan, the largest U.S. town on the U.S . Canada border, and the Wayne County seat. Detroit municipality had an estimated population of 672,662, making it the 23rd-most populated city in the U.S. Considered a major cultural centre, Detroit is renowned for its musical contributions and as a center for art, architecture and design. Detroit is one of the four main straits that link the Great Lakes system to the Saint Lawrence Seaway, a major port on the Detroit River. The most heavily represented sectors are especially automotive, finance, technology, and health care manufacturing. The major Detroit-based companies include General Motors, Quicken Loans, and Ally Financial.